Rhonda’s Award 2024
Principal Investigator: Elizabeth Stover MD, PhD, Dana-Farber Cancer Institute
Institute Collaborators: Joan Brugge PhD, Harvard Medical School; Ursula Matulonis MD, Dana-Farber Cancer Institute
Aim 1: Characterize expression of apoptosis proteins in MOC cell lines and patient samples
Aim 2: Determine sensitivity of MOC cell lines to inhibitors of BCL-2 family pro-survival proteins and other cell death related compounds using viability assays and BH3 profiling of apoptotic priming
Aim 3: Evaluate the efficacy of combining inhibitors of BCL-2 family pro-survival proteins with chemotherapy and targeted agents in MOC cell lines
Dr. Elizabeth Stover Biography
Dr. Stover received her M.D. (2009) and Ph.D. (2007) from Harvard Medical School, with Ph.D. research in the biology of hematologic malignancies. She completed an internal medicine residency at Brigham and Women’s Hospital in 2011 and a Hematology/Oncology fellowship at Dana-Farber Cancer Institute and Massachusetts General Hospital in 2016.Currently, Dr. Stover is an Assistant Professor of Medicine at Harvard Medical School and a medical oncologist in the Division of Gynecologic Oncology. She is engaged in laboratory and translational research focusing on genomics and drug resistance in ovarian cancer and other gynecologic cancers.